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Flying in the face of aging

December 16, 2013 The Methuselah fruit fly lives for about four months – four times longer than an ordinary fruit fly. They’re also more vigorous. “They beat up the other flies and take their women...

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Herbal Supplement Extends Life Span Under Some Environmental Conditions

April 16, 2015 Abstract Genetic studies indicate that aging is modulated by a great number of genetic pathways. We have used Drosophila longevity and stress assays to test a multipath intervention...

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Laboratory Summary Report: 2011

Winter Quarter We collected the remaining O flies (“RO”) from the Rose lab at UCI, and Genescient now houses ALL O flies. In our Gen9 experiment, we tested MX-100 again. This time, we included a...

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Laboratory Summary Report: 2012

Winter Quarter Dr. Robin Mockett, at University of Alabama, confirmed the longevity benefits of MX-100 on his fruit flies under certain conditions. We begin writing the MX-100 paper, reporting these...

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Genome-wide analysis of long-term evolutionary domestication in Drosophila...

December 22, 2016 Abstract Experimental evolutionary genomics now allows biologists to test fundamental theories concerning the genetic basis of adaptation. We have conducted one of the longest...

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Laboratory Summary Report: 2016

Winter Quarter Our Gen31 experiment assays the transgenic Tau Alzheimer’s Disease (AD) flies and our “B” flies with MX100a, memantine (Namenda), and combinations of the two therapies. Memantine...

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Laboratory Summary Report: 2017

Winter Quarter Work continues on a paper that describes our transgenic Alzheimer’s fly model and the human pilot study we conducted as a result of studies using that model. Some preliminary data...

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Multipath Natural Product Supplement Suppresses Dementia Symptoms in...

January 18, 2018 Abstract Background: Numerous reports on Alzheimer’s Disease (AD) indicate that AD has many biochemical pathways. However, most AD treatments have targeted a single pathway such as...

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Botanical Mixture Stabilizes Cognitive Function in Patients with Mild and...

August 17, 2018 Abstract Context: Currently, there is no treatment that can stop the progression of Alzheimer’s disease. We have used transgenic Drosophila melanogaster models and machine learning to...

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Laboratory Summary Report: 2018

Winter Quarter Our paper, “Multipath Natural Product Suplement Supresses Dementia Symptoms in Amyloid-B and Tau Transgenic Drosophila” is published in The Journal of Biology and Medical Research in...

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